Istanbul earns fifth for the Blue Mosque, Topkapı Palace and the Bosphorus setting. The strait separates its European and Asian sides: it qualifies geographically without being entirely European.

It beats Amsterdam on the contrast between monuments and the water; Barcelona takes fourth for our preferred blend of architecture, old streets and seaside time. Start with a historic-area day, then give the Bosphorus a separate focus. If that cross-continental setting is your main reason to travel, Istanbul can be your personal #1.

Sources: Go Türkiye · Photo: kallerna · CC BY-SA 4.0. Resized/recompressed; source license retained.